The Ecology of Prions
Zabel M and Ortega A. 2017. The Ecology of Prions. Microbiology and Molecular Biology Reviews
SUMMARY: Chronic wasting disease (CWD) affects cervids and is the only known prion disease readily transmitted among free-ranging wild animal populations in nature. The increasing spread and prevalence of CWD among cervid populations threaten the survival of deer and elk herds in North America, and potentially beyond. This review focuses on prion ecology, specifically that of CWD, and the current understanding of the role that the environment may play in disease propagation. We recount the discovery of CWD, discuss the role of the environment in indirect CWD transmission, and consider potentially relevant environmental reservoirs and vectors. We conclude by discussing how understanding the environmental persistence of CWD lends insight into transmission dynamics and potential management and mitigation strategies.
- Type
- Journal Article
- Authors
- Zabel, Mark; Ortega, Aimee
- Units
- ROMO
- Keywords
- cervids, chronic wasting disease, Chronicprions, Deer, Ecological and Environmental Phenomenaprions, ecology, environment, plants, soil, transmission, Wasting Disease, water